BLOCK PAIN RECEPTORS WITH PROLEVIATE NO FURTHER A MYSTERY

Having identified the palmitoylation motif of APLNR, we designed a short substrate sequence to competitively inhibit the palmitoylation of endogenous APLNR. This competitive peptide, which targets the APLNR palmitoylation web site in combination with morphine, can inhibit the development of NCP, like pain incidence, microglial activation, and infla